1、科研项目: (1) 光敏剂的智能输送与释放及在肿瘤光动力治疗中的应用, 国家自然科学基金青年项目, 51703163, 2018/01-2020/12, 23万元, 主持. (2) 近红外光激发微环境响应型光敏剂传输载体的制备及在光动力治疗中的应用, 天津市自然科学基金面上项目, 18JCYBJC86700, 2018/10-2021/09, 10万元, 主持. 2、论文、专著: (1) Zheng He, Linlin Zhao, Qiang Zhang, Meijia Chang, Chenxi Li, Hesheng Zhang,Yan Lu, Yongsheng Chen, An acceptor-donor-acceptor structured small molecule for effective NIR triggered dual phototherapy of cancer, Advanced Functional Materials, 2020, 30, 1910301. (2) Linlin Zhao, Jongseon Choi, Yan Lu, and So Yeon Kim, Targeted Photodynamic therapy activities of surface-enhanced raman scattering-active theranostic system based on folate/hyaluronic acid-functionalized gold nanochains, Journal of Biomedical Nanotechnology, 2019, 15, 544-554. (3) Lihua Liu, Linlin Zhao, Dandan Cheng, Xinyi Yao, Yan Lu, Highly selective fluorescence sensing and imaging of ATP using a boronic acid groups-bearing polythiophene derivate, Polymers, 2019, 11, 1139. (4) Linlin Zhao, Tae-Hyun Kim, Hae-Won Kim, Jin-Chul Ahn, So Yeon Kim, Enhanced cellular uptake and phototoxicity of Verteporfin-conjugated gold nanoparticles as theranostic nanocarriers for targeted photodynamic therapy and imaging of cancers, Materials Science and Engineering C, 2016, 67, 611-622. (5) Linlin Zhao, Tae-Hyun Kim, Hae-Won Kim, Jin-Chul Ahn, So Yeon Kim, Surface-enhanced Raman scattering (SERS)-active gold nanochains for multiplex detection and photodynamic therapy of cancer, Acta Biomaterialia, 2015, 20, 155-164. (6) Linlin Zhao, Tae-Hyun Kim, Hae-Won Kim, So Yeon Kim, Pheophorbide a-Conjugated pH-Sensitive Nanoparticle Vectors for Highly Efficient Photodynamic Therapy of Cancer, International Journal of Polymeric Materials, 2015, 64(14) , 733-744. (7) Linlin Zhao, Hui-Jeong Gwon, Youn-Mook Lim, Young-Chang Nho, So Yeon Kim, Hyaluronic acid/chondroitin sulfate-based hydrogel prepared by gamma irradiation technique, Carbohydrate Polymers, 2014, 102, 598-605. (8) Linlin Zhao, Tae-Hyun Kim, Jin-Chul Ahn, Hae-Won Kim, So Yeon Kim, Highly efficient "theranostics" system based on surface-modified gold nanocarriers for imaging and photodynamic therapy of cancer, Journal of Materials Chemistry B, 2013, 1(42), 5806-5817. (9) Linlin Zhao, Luqing Shi, Jing Wang, Qiang Zhang, Xinlin Yang, Yan Lu, Degradable inorganic/polymer core-shell microspheres for ph-triggered release of indole-3-acetic acid, International Journal of Polymeric Materials and Polymeric Biomaterials, 2020, 69, 317-325. (10) Linlin Zhao, Tae-Hyun Kim, Kang Moo Huh, Hae-Won Kim, So Yeon Kim, Self-assembled photosensitizer-conjugated nanoparticles for targeted photodynamic therapy, Journal of Biomaterials Applications, 2013, 28(3), 434-447. 3、其他成果(奖励、专利等): (1) 一种活性氧刺激响应型纳米凝胶药物载体及其制备方法和应用,专利号:ZL2016111263103 (2) 基于共轭聚合物/金属离子复合物的L-半胱氨酸荧光探针及制备方法和应用,专利号:ZL2018106404986 |